From 2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate to cis-2-Hydroxypenta-2,4-dienoate and Phthalate

Graphic of the reaction.

Medline reference

Wattiau P, Bastiaens L, van Herwijnen R, Daal L, Parsons JR, Renard ME, Springael D, Cornelis GR. Res Microbiol (2001) 152(10): 861-72.

Search Medline for 9-fluorenone biodegradation.

58 citations on June 26, 2008.

                              2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate                              
                                                        |
                                                        |  H2O
  2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate | /
                                              hydrolase |/
                                                3.7.1.- | Search GenBank, 1 hits on Jun. 27, 2008
                                                        |\
                                                 ExPASy | \
                                                        |  H+
                                                        v
                                   cis-2-Hydroxypenta-2,4-dienoate + Phthalate                                   

UM-BBD Biotransformation rules in accord with this reaction:

1-Aldo/keto-2,4-diene-5-ol -----> Carboxylate + 1-ene-4-one (bt0040)

Page Author(s): Lynda Ellis
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r1042.
It was generated on November 24, 2009 10:47:02 PM CST.

© 2009, University of Minnesota.