From 2,3-Dihydroxy-2'-carboxybiphenyl to 2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate

Graphic of the reaction.

Medline reference

Wattiau P, Bastiaens L, van Herwijnen R, Daal L, Parsons JR, Renard ME, Springael D, Cornelis GR. Res Microbiol (2001) 152(10): 861-72.

Search Medline for dihydroxybiphenyl dioxygenation.

9 citations on June 26, 2008.

                   2,3-Dihydroxy-2'-carboxybiphenyl                    
                                   |
                                   |  O2
  2,3-dihydroxy-2'-carboxybiphenyl | /
                   1,2-dioxygenase |/
                          1.13.-.- |
                                   |\
                            ExPASy | \
                                   |  H+
                                   v
         2-Hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate         

UM-BBD Biotransformation rules in accord with this reaction:

vic-Dihydroxybenzenoid -----> extradiol ring cleavage (bt0008)

Page Author(s): Lynda Ellis
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r1041.
It was generated on November 24, 2009 10:21:55 PM CST.

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