From 1-Hydro-1,1a-dihydroxy-9-fluorenone to 2,3-Dihydroxy-2'-carboxybiphenyl

Graphic of the reaction.

Medline reference
Wattiau P, Bastiaens L, van Herwijnen R, Daal L, Parsons JR, Renard ME, Springael D, Cornelis GR. Res Microbiol (2001) 152(10): 861-72.

Search Medline for 9-fluorenone angular dioxygenation.
6 citations on June 26, 2008. 
                     1-Hydro-1,1a-dihydroxy-9-fluorenone                     
                                      |
                                      |  H2O
  1-hydro-1,1a-dihydroxy-9-fluorenone | /
                        dehydrogenase |/
                              1.3.-.- |
                                      |\
                               ExPASy | \
                                      |  3H+ + 2e-
                                      v
                      2,3-Dihydroxy-2'-carboxybiphenyl
Generate a pathway starting from this reaction.

UM-BBD Biotransformation rules in accord with this reaction:
Hemiacetal-like polynuclear aromatic derivative -----> cleavage at connecting atom (bt0197)
[Fluorene] [BBD Main Menu]

Page Author(s): Lynda Ellis
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r1040.
It was generated on November 24, 2009 10:59:39 PM CST. 

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