From Salicylate to Gentisate

Graphic of the reaction.

Medline reference
Zhou NY, Al-Dulayymi J, Baird MS, Williams PA. J Bacteriol (2002) 184(6): 1547-55.

Search Medline for salicylate 5-hydroxylase.
86 citations on June 26, 2008. 
           Salicylate            
                |
                |  O2 + NAD(P)H + H+
     salicylate | /
  5-hydroxylase |/
      1.14.13.- | Search GenBank, 28 hits on Jun. 27, 2008
                |\
         ExPASy | \
                |  H2O + NAD(P)+
                v
            Gentisate
Generate a pathway starting from this reaction.

UM-BBD Biotransformation rules in accord with this reaction:
1-Hydroxy-4-unsubstituted benzenoid -----> 1,4-Dihydroxybenzenoid derivative (bt0064)
[Naphthalene] [BBD Main Menu]

Page Author(s): Carla Essenberg
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r1034.
It was generated on November 24, 2009 7:44:00 AM CST. 

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