From Carbazole to 2'-Aminobiphenyl-2,3-diol

Graphic of the reaction.
Medline reference: Sato SI, Ouchiyama N, Kimura T, Nojiri H, Yamane H, Omori T. J Bacteriol (1997) 179(15): 4841-9.
Search Medline for carbazole dioxygenase.: 49 citations on June 26, 2008.

               Carbazole               
                   |
                   |  NADH + O₂ + H⁺
         carbazole | /
  1,9a-dioxygenase |/
         1.14.12.- | Search GenBank, 17 hits on Sep. 25, 2009
                   |\
            ExPASy | \
                   |  NAD⁺
                   v
       2'-Aminobiphenyl-2,3-diol

Generate a pathway starting from this reaction.

UM-BBD Biotransformation rules in accord with this reaction:: polynuclear Aromatic system -----> 1,2-dioxygenation and cleavage at connecting atom (bt0374)

[Carbazole] [BBD Main Menu]

Page Author(s): Thanh Trinh
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r0456.
It was generated on November 24, 2009 7:40:59 AM CST.

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