From 4-Sulfobenzoate to 3,4-Dihydroxybenzoate

Graphic of the reaction.

Graphic of its mechanism.

Medline reference
Locher HH, Leisinger T, Cook AM. Biochem J (1991) 274 ( Pt 3): 833-42.

Search Medline for sulfobenzoate dioxygenase.
5 citations on June 26, 2008. 
           4-Sulfobenzoate           
                  |
                  |  NADH + O2
  4-sulfobenzoate | /
  3,4-dioxygenase |/
        1.14.12.8 | Search GenBank, 2 hits on Jun. 27, 2008
            Kyoto |\
           ExPASy | \
                  |  NAD+ + SO32-
                  v
        3,4-Dihydroxybenzoate
Generate a pathway starting from this reaction.

UM-BBD Biotransformation rules in accord with this reaction:
1-Sulfo-2-unsubstituted aromatic -----> vic-Dihydroxyaromatic + Sulfonite (bt0128)
[Toluene-4-sulfonate] [BBD Main Menu]

Page Author(s): Kathryn Eisenmann and Ryan McLeish
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r0293.
It was generated on November 24, 2009 7:30:13 AM CST. 

© 2009, University of Minnesota.