From 5-Chloro-2-hydroxymuconic semialdehyde to 5-Chloro-2-oxopent-4-enoate

Graphic of the reaction.

Medline reference
Hollender J, Hopp J, Dott W. Appl Environ Microbiol (1997) 63(11): 4567-4572.

Search Medline for 2-hydroxymuconate semialdehyde hydrolase.
22 citations on June 26, 2008. 
              5-Chloro-2-hydroxymuconic semialdehyde               
                                 |
                                 |  H2O
  2-hydroxymuconate semialdehyde | /
                       hydrolase |/
                         3.7.1.9 | Search GenBank, 35 hits on Sep. 22, 2008
                           Kyoto |\
                          ExPASy | \
                                 |  CHO2H
                                 v
                    5-Chloro-2-oxopent-4-enoate
Generate a pathway starting from this reaction.

UM-BBD Biotransformation rules in accord with this reaction:
1-Aldo/keto-2,4-diene-5-ol -----> Carboxylate + 1-ene-4-one (bt0040)
[2,4-Dichlorophenoxyacetic Acid] [BBD Main Menu]

Page Author(s): Brian Hill, Carla Essenberg, Michael Turnbull and Lynda Ellis
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r0289.
It was generated on November 24, 2009 4:04:55 AM CST. 

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