From 3-Chloro-cis,cis-muconate to cis-4-Carboxymethylenebut-2-en-4-olide

Graphic of the reaction.

Medline reference
Hammer A, Hildenbrand T, Hoier H, Ngai KL, Schlomann M, Stezowski JJ. J Mol Biol (1993) 232(1): 305-7.

Search Medline for chloromuconate cycloisomerase.
43 citations on June 26, 2008.

         3-Chloro-cis,cis-muconate         
                     |
                     |
      chloromuconate |
      cycloisomerase |
             5.5.1.7 | Search GenBank, 111 hits on Sep. 22, 2008
               Kyoto |\
              ExPASy | \
                     |  HCl
                     v
  cis-4-Carboxymethylenebut-2-en-4-olide   
Generate a pathway starting from this reaction.

UM-BBD Biotransformation rules in accord with this reaction:
3-Halo-cis,cis-muconate derivative -----> cis-4-Carboxymethylenebut-2-en-4-olide derivative (bt0206)

[2,4-Dichlorophenoxyacetic Acid] [BBD Main Menu]

Page Author(s): Brian Hill
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r0285.
It was generated on November 24, 2009 7:30:43 AM CST.

© 2009, University of Minnesota.