From Toluene to 4-Hydroxytoluene

Graphic of the reaction.

Medline reference
Yen KM, Karl MR, Blatt LM, Simon MJ, Winter RB, Fausset PR, Lu HS, Harcourt AA, Chen KK. J Bacteriol (1991) 173(17): 5315-27.

Search Medline for toluene 4-monooxygenase.
58 citations on October 20, 2008.
               Toluene               
                  |
                  |  NADH + H+ + O2
          toluene | /
  4-monooxygenase |/
        1.14.13.- | Search GenBank, 29 hits on Jun. 27, 2008
                  |\
           ExPASy | \
                  |  NAD+ + H2O
                  v
          4-Hydroxytoluene           
Generate a pathway starting from this reaction.

UM-BBD Biotransformation rules in accord with this reaction:
monosubstituted Benzenoid -----> Add p-OH (bt0013)

[Toluene] [BBD Main Menu]

Page Author(s): Yuemo Zeng
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r0255.
It was generated on November 24, 2009 10:46:36 PM CST.

© 2009, University of Minnesota.