From Toluene to Toluene-cis-1,2-dihydrodiol

Graphic of the reaction.

Medline reference
Wackett LP, Kwart LD, Gibson DT. Biochemistry (1988) 27(4): 1360-7.

Search Medline titles for toluene dioxygenase.
35 citations on June 26, 2008.

Reactions of toluene dioxygenase
            Toluene             
                |
                |  NADH + H+ + O2
        toluene | /
    dioxygenase |/
     1.14.12.11 | Search GenBank, 10 hits on Sep. 22, 2008
          Kyoto |\
         ExPASy | \
                |  NAD+
                v
  Toluene-cis-1,2-dihydrodiol   
Generate a pathway starting from this reaction.

UM-BBD Biotransformation rules in accord with this reaction:
mono-carbon-substituted Benzenoid -----> 1-substituted-2,3-dihydrodihydroxy Benzenoid (bt0369)

[Toluene] [BBD Main Menu]

Page Author(s): Yuemo Zeng
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r0253.
It was generated on November 24, 2009 7:36:38 AM CST.

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