From Dibenzothiophene-5-oxide to Dibenzothiophene-5,5-dioxide

Graphic of the reaction.

Medline reference
Gray KA, Pogrebinsky OS, Mrachko GT, Xi L, Monticello DJ, Squires CH. Nat Biotechnol (1996) 14(13): 1705-9.

Search Medline for dibenzothiophene biodesulfurization.
62 citations on October 20, 2008.
    Dibenzothiophene-5-oxide     
                |
                |  O2 + NADH
            DBT | /
  monooxygenase |/
      1.14.13.- | Search GenBank, 13 hits on Aug. 25, 2009
                |\
         ExPASy | \
                |  OH- + NAD+
                v
  Dibenzothiophene-5,5-dioxide   
Generate a pathway starting from this reaction.

UM-BBD Biotransformation rules in accord with this reaction:
di-[C,O]-substituted Sulfoxide -----> di-[C,O]-substituted Sulfone (bt0193)

[Dibenzothiophene Desulfurization] [BBD Main Menu]

Page Author(s): Margie Romine and Kevin Gray
August 14, 2005 Contact Us

This is the UM-BBD reaction, reacID# r0038.
It was generated on November 24, 2009 7:29:21 AM CST.

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