2-Nitropropane Pathway Map

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This pathway was contributed by Sathit Niratisai and Thanh Trinh, University of Minnesota, and completed by Jingfeng Feng, University of Minnesota.

2-Nitropropane is a clear, colorless liquid with a mild, fruity odor, that can cause acute liver damage (Borges et al., 2006). The primary routes of potential human exposure to 2-nitropropane are inhalation, ingestion, and skin contact.

This pathway is based on the biodegradation carried out by fungal organisms (Gorlatova et al., 1998).

The following is a text-format 2-Nitropropane pathway map. Organisms which can initiate the pathway are given, but the other organisms may also carry out later steps. Follow the links for more information on compounds or reactions. This map is also available in graphic (4k) format.

                  2-Nitropropane 
                 Neurospora crassa
                Fusarium oxysporum 
           Williopsis saturnus var. mrakii
                        |
                        |
                        | 2-nitropropane
                        | dioxygenase
                        |
                        v
                     Acetone 
                        |
                        |
                        | 
                        | 
                        |
                        v
                  Intermediary
                   Metabolism  
                     (KEGG)

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Page Author(s): Thanh Trinh and Jingfeng Feng

April 25, 2008 Contact Us

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