This pathway was completed by Jingfeng Feng, University of Minnesota.
Benzoate is a colorless or light yellow transparent liquid with very faint floral odor. It is an excellent solvent of synthetic musks and vanillin, and a fixative in bouguet perfumes. Benzoate is a common intermediate in the anaerobic metabolism of aromatic compounds, documented elsewhere in the UMBBD. There are also many studies of its aerobic metabolism (Harayama et al., 1991 and Sahasrabudhe et al., 1985).
2-chlorobenzoate biodegradation is also included on this pathway map. It is used as a preservative for glues and paints and an intermediate in the manufacture of fungicides, dyes, pharmaceuticals and other organic chemicals.
The following is a text-format benzoate degradation pathway map. Organisms which can initiate the pathway are given, but other organisms may also carry out later steps. Follow the links for more information on compounds or reactions. This map is also available in graphic (7k) format.
from the
Benzonitrile Pathway
Toluene Pathway
Biphenyl Pathway
|
|
+---------------+---------------+
| |
v v
Benzoate Benzoate
Pseudomonas putida Pseudomonas sp.
| Aspergillus niger
| Rhodotorula graminis
| |
| |
| benzoate | benzoate
| dioxygenase | 4-monooxygenase
| |
v v to the
cis-1,6-Dihydroxy-2,4- 4-Hydroxybenzoate ---> 2,4-Dichlorobenzoate
cyclohexadiene-1- Pathway
carboxylic acid
|
|
| benzoate cis-diol
| dehydrogenase
|
v
Catechol <------------------------ 2-Chlorobenzoate
| 2-chlorobenzoate Burkholderia cepacia 2CBS
| 1,2-dioxygenase Pseudomonas aeruginosa
| Aspergillus niger
v Pseudomonas sp. CPE2
to the
Nitrobenzene Pathway
Page Author(s): Jingfeng Feng
April 25, 2008 Contact Us
© 2008, University of Minnesota. All rights reserved. http://umbbd.msi.umn.edu/benz2/benz2_map.html